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34 electrospun nanofibers in drug delivery the aim of designing an electrospun nfs in drug delivery system is to control drug release over a definite period depending on medical conditions the rate of drug release can be tailored on the basis of fiber diameter porosity and drug binding mechanisms for various applicationsin this volume we have explored in detail the use of polymer nanofibres in drug delivery the majority of attention was paid to electrospinning since this is the route which has received by far the most research attention for fabricating drug loaded fibresadvantages of nanofibers in drug delivery26 28 explored for their ability to encapsulate and deliver bioactive molecules for therapeutic applications increased surface area dissolution rate of a drug increases enhanced solubility increased oral bioavailability more rapid onset of therapeutic action less amount of dose required site nanofibers for drug delivery incorporation and release of model molecules influence of molecular weight and polymer structure jakub hrib 1 jakub sirc 1 radka hobzova 1 zuzana hampejsova 2 zuzana bosakova 2 marcela munzarova 3 and jiri michalek 1 kerstin koch associate editorin recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering nanofibres in drug delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery and to explain to them how to prepare fibres in the laboratory

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