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34 electrospun nanofibers in drug delivery the aim of designing an electrospun nfs in drug delivery system is to control drug release over a definite period depending on medical conditions the rate of drug release can be tailored on the basis of fiber diameter porosity and drug binding mechanisms for various applicationsnanofibers for drug delivery incorporation and release of model molecules influence of molecular weight and polymer structure jakub hrib 1 jakub sirc 1 radka hobzova 1 zuzana hampejsova 2 zuzana bosakova 2 marcela munzarova 3 and jiri michalek 1 kerstin koch associate editorin this volume we have explored in detail the use of polymer nanofibres in drug delivery the majority of attention was paid to electrospinning since this is the route which has received by far the most research attention for fabricating drug loaded fibresadvantages of nanofibers in drug delivery26 28 explored for their ability to encapsulate and deliver bioactive molecules for therapeutic applications increased surface area dissolution rate of a drug increases enhanced solubility increased oral bioavailability more rapid onset of therapeutic action less amount of dose required site nanofibres in drug delivery aims to outline to new researchers in the field the utility of nanofibers in drug delivery and to explain to them how to prepare fibers in the laboratory the book begins with a brief discussion of the main concepts in pharmaceutical science

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